New Techniques of Resection and Long- Term Survival for Cholangiocarcinoma
نویسندگان
چکیده
Cholangiocarcinoma is uncommon cancer with an incidence 1-2/100 000 in the USA. Predisposing diseases for developing of cholangiocarcinoma include primary sclerosing cholangitis (PSC), congenital biliary cystic disease and hepatolithiasis with biliary infestations by Clonorchis siniensis, also called recurrent pyogenic cholangiohepatatis ( mainly encountered in Japan and Southwest Asia). The majority of bile duct tumors is relatively slow-growing. However, this progression can be rapid in some patients. Blood-borne metastases are uncommon, but nodal metastases, perineural and lymphatic involvement as well as subepithelial spread are very common.
منابع مشابه
Liver Transplantation for Cholangiocarcinoma
The treatment of intraand extrahepatic cholangiocarcinomas remains a medical challenge. Due to the poor efficacy of conventional chemotherapy, surgical treatment modalities represent the only chance of attaining long-term survival and cure. The introduction of new procedures, in particular extended liver resections – which were enabled by increasing surgical expertise and the implementation of ...
متن کاملMetachronous cholangiocarcinoma 13 years post resection of choledochal cyst—is long-term follow-up useful?: a case study and review of the literature
BACKGROUND Patients with congenital choledochal cyst are at risk of the development of hepatobiliary malignancy, with recommended treatment of choledochal cyst being surgical excision. The development of cholangiocarcinoma more than 10 years after excision of choledochal cysts is rare, with less than 21 cases reported in the literature from 1972 to 2014. This is the first reported case of metac...
متن کاملSurgical procedure and long-term survival of hilar cholangiocarcinoma.
OBJECTIVE The aim of this study was to identify the influencing factors related to outcome of patients with hilar cholangiocarcinoma. METHODS From January 1999 to January 2009, 204 cases of hilar cholangiocarcinoma undergoing surgery were analyzed retrospectively. Bismuth-Corlette classification showed type I in 18 patients, type II in 40, type IIIa in 65, type IIIb in 54, type IV in 27. Surv...
متن کاملStaging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma.
OBJECTIVE To analyze resectability and survival in patients with hilar cholangiocarcinoma according to a proposed preoperative staging scheme that fully integrates local, tumor-related factors. SUMMARY BACKGROUND DATA In patients with hilar cholangiocarcinoma, long-term survival depends critically on complete tumor resection. The current staging systems ignore factors related to local tumor e...
متن کاملA new era of surgical treatment of hilar cholangiocarcinoma: comparison of leading Eastern and Western centers Surgical treatment of hilar cholangiocarcinoma in the ‘‘new era’’: the Nagoya University experience
Objective To review our surgical experience with hilar cholangiocarcinoma in the ‘‘new era.’’ Methods The medical records of 428 patients with hilar cholangiocarcinoma who underwent treatment between 2001 and 2008 at the First Department of Surgery, the Nagoya University Hospital, were retrospectively reviewed. Results Of the 428 patients, 298 (70%) underwent surgical resection (R0, n = 220; R1...
متن کامل